If you are planning to leave your Depop shop unattended for a while make sure you let the community know.
At the moment, the best way to do so is to add a note in your bio, explaining that you're away and confirming when you'll next be back online to check-in on your shop.
Do also make sure to mark your items as sold or delete them so that no one is able to buy them when you're not around! If an item is active it can still be purchased, even if your bio says you are away.
Once you are back, just remember to set everything back as before.
Happy holidays and see you back soon!